The series on “Pencil Beam Scanning Particle Therapy” is edited by Chin-Cheng Chen from New York Proton Center, Dennis Mah from ProCure Proton Therapy Center, Chang Chang from California Proton Therapy Center, Joseph Tung-Chieh Chang from Chang Gung Memorial Hospital and Nancy Y. Lee from Memorial Sloan-Kettering Cancer Center.

Chin-Cheng Chen, PhD, DABR
Senior Medical Physicist, New York Proton Center, New York, New York, U.S.A.

Dr. Chen is the lead medical physicist in quality assurance, and the lead medical physicist of Breast and Head & Neck clinical services at New York Proton Center. He received the PhD degrees from National Tsing-Hua University in Taiwan. Following a residency and post-doctoral fellowship at Montefiore Medical Center/Albert Einstein College of Medicine in New York, Dr. Chen was a medical physicist at NewYork-Presbyterian Hospital/Columbia University Medical Center in New York, ProCure Proton Therapy Center in New Jersey and then at the Johns Hopkins Proton Therapy Center in Washington, DC. He joined the New York Proton Center in 2020. Dr. Chen is experienced in proton Pencil Beam Scanning commissioning, treatment planning, and quality assurance. Dr. Chen currently serves as the Member of the Treatment Efficiency Subcommittee of Particle Therapy Co-Operative Group (PTCOG), and the Guest Member of Task Group No. 350 of American Association of Physicists in Medicine (AAPM). He has authored peer-reviewed publications, presentations, and book chapters. He is also a reviewer of major scientific journals, including Medical Physics, Radiotherapy and Oncology, International Journal of Particle Therapy, and Journal of Applied Clinical Medical Physics.

Dennis Mah, PhD, DABR
Director of Medical Physics and Dosimetry, ProCure Proton Therapy Center, Somerset, New Jersey, U.S.A.

Dr Mah is the founding Director of Medical Physics at the ProCure Proton Therapy Center in Somerset NJ, USA. Dr. Mah completed his PhD at the University of Toronto, Canada in Medical Physics. He completed a clinical fellowship at Memorial Sloan Kettering Cancer Center in New York City. Dr. Mah subsequently held faculty positions at Fox Chase Cancer Center in Philadelphia, Columbia University in New York, and Montefiore/Einstein in New York where he also served as physics director. He has published over 45 peer reviewed papers, over 100 abstracts and one book chapter. Dr Mah has a longstanding interest in motion management, delivery uncertainties and new technologies.

Chang Chang, PhD, DABR
Associate Professor and Associate Division Director, Department of Radiation Medicine and Applied Sciences, University of California San Diego, Director of Physics, California Proton Therapy Center, San Diego, California, U.S.A.

Dr. Chang is an Associate Professor, Associate Division Director of Proton Therapy and Director of Physics at the California Proton Therapy Center, an Affiliate of the UC San Diego Health Cancer Network. A dedicated Proton Physicist, Dr. Chang oversees all technical aspects of the Proton Center including treatment planning and quality assurance as well as supervising the technical operations of the center. He also oversees the recruitment and mentorship of the medical physicists at the Proton Center. He has considerable experience in proton therapy, having worked at the ProCure Proton Therapy Center in Somerset New Jersey and later serving as the Director of Physics at the Texas Center for Proton Therapy in Irving Texas. Dr. Chang oversees the clinical rotations of the UC San Diego Medical Physics Residents rotating at the Proton Center and is involved with the Medical Physics and Medical Residency Didactic Programs. He has published over 30 journal articles and book chapters focused on all aspects of proton therapy.

Joseph Tung-Chieh Chang, MD, M.H.A.
Professor, Director, Proton and Radiation Therapy Center, Chang Gung Memorial Hospital, Linkou Medical Center; Department of Medicine, School of Medicine, Chang Gung University, Taoyuan, Taiwan, R.O.C.

Dr. Joseph Tung-Chieh Chang, MD, MHA, is a board-certified radiation oncologist, sub-specializing in head and neck cancer, breast cancer, and gastrointestinal cancers. He served as Chairman of the Department of Radiation Oncology and is the Director of Proton and Radiation Therapy Center, Chang Gung Memorial Hospital, Linkou Medical Center, and a professor in Chang Gung University, Taiwan. His expertise focuses on IMPT Radiotherapy, Qualify of Life, Medical Economy, and Translational Tumor Biology. With plenty of clinical experiences, Dr. Chang has successfully treated thousands of patients by IMRT/VMAT and hundreds of patients by IMPT. He is also an active member in several professional communities, including TASTRO, ASTRO, ASCO, PTOG. To date, Dr. Chang has published more than 200 peer-reviewed papers and book chapters in all aspects related to radiotherapy.

Nancy Y. Lee, MD, FASTRO
Director of Head and Neck Cancer, Proton Service Chief, Vice Chairman for Experimental Therapeutics Department of Radiation Oncology Member, Memorial Sloan-Kettering Cancer Center, New York, New York, U.S.A.

Dr Lee’s research focus is in developing novel approaches personalized treatment head and neck cancers. This includes dose reduction in selected head and neck cancers, assessing biologically targeted therapies and using biomarkers, optimizing use of IMRT, SBRT and proton therapy including FLASH, combining immunotherapy with radiation, and targeted novel therapeutics with radiation therapy including DNA repair inhibitors. She currently serves on the editorial board of the Journal of Radiation Oncology, Frontiers in Oncology, Oral Oncology and Cancers. She leads several RTOG protocols as national PI.Dr. Lee has been PI on multiple NIH, institution and corporate grants and has published over 200 peer reviewed papers and over 45 book chapters. Dr. Lee has served on national and international scientific and advisory committees. Her numerous national and international honors and recognition include Fellowship the American Society of Radiation Oncology (FASTRO). Dr Lee has a keen interest in proton therapy for head and neck cancers and has treated several hundred patients with protons.

Series outline:

1. Advanced proton pencil beam scanning (review)
2. Pencil beam scanning carbon ion radiation therapy (review)
3. Pencil beam scanning proton FLASH therapy (review)
4. Clinical experience of proton pencil beam scanning SBRT (review)
5. RBE modeling and LET based optimization in pencil beam scanning proton planning for CNS and HN patients
6. Dosimetric study of breast patient using proton pencil beam scanning with deep-inspiration breath hold and free breathing
7. Bladder volumetric control using ultrasound bladder scanner for prostate patients
8. Feasibility assessment of proton treatment for ventricular tachycardia disease- treatment planning comparison study
9. Energy dependence of LiF detectors in proton therapy beam dosimetry
10. A retrospective photon and proton planning comparison of bilateral breast patients
11. Total scalp irradiation using proton pencil beam scanning

Disclosure:
The series “Pencil Beam Scanning Particle Therapy” was commissioned by the editorial office, Therapeutic Radiology and Oncology without any sponsorship or funding. Dr. Chin-Cheng Chen, Dr. Dennis Mah, Dr. Chang Chang, Dr. Joseph Tung-Chieh Chang and Dr. Nancy Y. Lee are serving as the unpaid Guest Editors for the series.