AB005. Radioprotection assessment of an accelerator-based boron neutron capture therapy lab
Abstract

AB005. Radioprotection assessment of an accelerator-based boron neutron capture therapy lab

María Eugenia Capoulat1,2,3, Andrés Juan Kreiner1,2,3

1Department of Accelerator Technology and Applications, National Atomic Energy Commission (CNEA), Buenos Aires, Argentina; 2National Scientific and Technical Research Council (CONICET), Buenos Aires, Argentina; 3School of Sciences and Technology, National University of San Martín (UNSAM), Buenos Aires, Argentina

Correspondence to: María Eugenia Capoulat, PhD. Department of Accelerator Technology and Applications, National Atomic Energy Commission (CNEA), Av. Gral. Paz 1499, B1650KNA San Martín, Buenos Aires, Argentina; National Scientific and Technical Research Council (CONICET), Buenos Aires, Argentina; School of Sciences and Technology, National University of San Martín (UNSAM), Buenos Aires, Argentina. Email: mcapoulat@gmail.com; capoulat@tandar.cnea.gov.ar.

Background: An Accelerator Development Lab (LDA) is under advanced construction at the National Atomic Energy Commission (CNEA), Argentina. At its core, the LDA holds a high-current/low-energy deuteron accelerator and the future patient irradiation room. Surrounding them are the control room, workshops, and other public areas. A 1.45-MV electro-static-quadrupole accelerator placed in the accelerator room will generate a 30-mA deuteron beam to be transported to a 13C or 9Be target, physically placed at the irradiation room inside of a beam shaping assembly (BSA). On the target, 5–5.7×1012 neutrons/s with energies up to ~6 MeV are produced by a (d,n) reaction (~70% of the intensity is <1 MeV). The BSA is made up of Al, Teflon®, Pb, and boronated paraffin. The radiation sources at the LDA are (I) neutrons, (II) prompt gamma-rays from neutron-induced reactions, (III) X-rays produced in the accelerator column, and (IV) delayed gamma-rays from the decay of activated materials. The objective of this work is to estimate occupational and public doses both during and after accelerator operation and, based on these results, to establish a preliminary radiological zoning of the facility. Effective doses during routine operation were calculated throughout the LDA to support this assessment.

Methods: Neutron and photon fluxes were simulated with the MCNP6 code. Flux-to-effective dose factors were taken from the Publication 116 of the International Commission on Radiological Protection (ICRP-116). Reaction cross-sections from evaluated databases were used to calculate induced radioactivity. Routinary operation is planned as 8 hours of irradiation followed by 16 hours of downtime, totalizing 2,000 hours of irradiation per year. The adopted dose restrictions (ARs) are 0.1 and 6 mSv/y for the public and workers, respectively. Total doses are the sum of the contributions of sources 1–4.

Results: Doses during irradiation are 1 and 42 mSv/h in the accelerator and the irradiation rooms, respectively. In the peripheral rooms, doses are <0.050 mSv/y, well below the public’s AR. Right after shutting down the accelerator and next to the BSA (i.e., the most activated element), the dose is 2 mSv/h, and decays below the worker’s AR 7 hours after.

Conclusions: Effective doses on routinary operation were calculated along the LDA. In the peripheral rooms (where the public or workers will stay during irradiation), the doses fit the public’s AR, hence, can be classified as public access areas. The irradiation and the accelerator room must be classified as controlled areas, with access forbidden during irradiation and time-limited during the first hours of downtime.

Keywords: Accelerator based-boron neutron capture therapy; electrostatic-quadrupole-accelerator; induced radioactivity; radiation protection


Acknowledgments

None.


Footnote

Funding: None.

Conflicts of Interest: Both authors have completed the ICMJE uniform disclosure form (available at https://tro.amegroups.com/article/view/10.21037/tro-25-ab005/coif). Both M.E.C. and A.J.K. are employees of the National Atomic Energy Commission (CNEA), Argentina. The authors have no other conflicts of interest to declare.

Ethical Statement: The authors are accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved. Ethical approval was not required for this study because it did not involve human or animal participants, nor did it entail the use of personal data.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the noncommercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0/.


doi: 10.21037/tro-25-ab005
Cite this abstract as: Capoulat ME, Kreiner AJ. AB005. Radioprotection assessment of an accelerator-based boron neutron capture therapy lab. Ther Radiol Oncol 2025;9:AB005.

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