@article{TRO4424,
author = {Kashmiri L. Chopra and Paul Leo and Christopher Kabat and Durg Vijay Rai and Jaiteerth S. Avadhani and Than Singh Kehwar and Anil Sethi},
title = {Evaluation of dose calculation accuracy of treatment planning systems in the presence of tissue heterogeneities},
journal = {Therapeutic Radiology and Oncology},
volume = {2},
number = {0},
year = {2018},
keywords = {},
abstract = {Background: Accuracy of five dose calculation algorithms within three treatment planning systems (TPS): BrainLAB iPlan 4.2 (BL: pencil beam and Monte Carlo), Philips Pinnacle (PL: Collapsed Cone Calculation, CCC), and Varian Eclipse (VR: AAA and Acuros XB) is investigated in this multi-institutional study.
Methods: A Monte-Carlo based TPS (BL) was first validated against benchmark measurements in heterogeneous-slab phantoms consisting of tissue-equivalent plastic, lung-equivalent cork, and bone density materials. Ion chamber/EDR film measurements of depth-dose and dose-profiles for 6MV enface photons in a range of field-sizes (12 mm × 12 mm – 60 mm × 60 mm) were performed. A common CT dataset for each phantom was sent to four participating institutions. Measured versus calculated dose differences for all dose algorithms considered in this study were quantified using two dose-profile indices: Ddiff within the central 80% of photon field, and Dspill for dose outside the field-edge (50–10% dose).
Results: BrainLAB TPS BL: MC and measured doses agreed well (Ddiff },
issn = {2616-2768}, url = {https://tro.amegroups.org/article/view/4424}
}